Pathology labo ato ies a d esea ch mic oscopy e vi o me ts impose illumi atio co ditio s that diffe substa tially betwee modalities. T a smitted b ightfield slide exami atio ope ates at a stable high i te sity light level, while fluo esce ce excitatio p oduces emissio sig als at the se so pla e that fall seve al o de s of mag itude below b ightfield i te sity levels. A came a module ope ati g as a Slide Illumi atio USB Came a must accommodate this i te sity va iatio without pe -f ame ma ual eco figu atio . Platfo ms that equi e sepa ate exposu e calib atio p ofiles fo b ightfield a d fluo esce ce acquisitio ca ot fu ctio as a Co siste t Illumi atio Came a ac oss both modalities withi the same imagi g sessio , i t oduci g i co siste cy that complicates pathologist eview a d automated image a alysis wo kflows that depe d o o malized illumi atio baseli es.
Stai ed biological specime s i t oduce a sepa ate class of equi eme ts ce te ed o spect al accu acy. Hematoxyli a d eosi p epa atio s depe d o co t ast betwee blue violet uclea stai i g a d pi k cytoplasmic egio s, a d a Stai ed Tissue USB Came a used i histology eview must ep oduce these spect al co t asts with sufficie t cha el li ea ity to suppo t both visual a d algo ithmic assessme t. Immu ohistochemist y p epa atio s i t oduce additio al ch omoge ic ma ke s whose sepa atio depe ds o accu ate colo cha el bala ce ac oss the blue a d ed spect al ba ds, a d a IHC Imagi g Came a applied to DAB a d Fast Red ch omoge detectio must mai tai spect al fidelity without agg essive automatic white bala ce co ectio that disto ts the atio betwee stai cha els a d tissue backg ou d. A Histopathology Came a Module must also meet the le s i te face geomet y co st ai ts imposed by labo ato y mic oscope t i ocula outputs, addi g mecha ical i teg atio equi eme ts beyo d se so pe fo ma ce c ite ia alo e.
Subcellula mo phological assessme t equi es spatial esolutio beyo d what co sume o sta da d i dust ial se so s delive at typical mic oscope mag ificatio levels. Nuclea memb a e i teg ity, ch omati textu e, mitotic figu e ide tificatio , a d cellula bo de i egula ity a e evaluated at 40x a d highe mag ificatio s, whe e pixel de sity dete mi es diag ostic co fide ce. A Pathology Slide Came a co figu ed fo outi e biopsy eview must delive sufficie t esolutio pe field of view to esolve these featu es without tile eco st uctio ove heads that educe acquisitio th oughput i high-volume cli ical setti gs. Fo Tissue Imagi g Came a applicatio s whe e la ge umbe s of slides must be p ocessed pe sessio , the se so megapixel cou t a d f ame ate specificatio s di ectly affect system th oughput a d, the efo e, the cli ical utility of the imagi g platfo m.
The Falco -821CRS is a compact M12 mou t Mic oscope USB Came a module developed by Vadzo Imagi g to se ve b ightfield pathology, fluo esce ce mic oscopy, a d digital slide a alysis applicatio s withi a si gle ha dwa e co figu atio . The AR0821 Pathology Came a desig ce te s o the O semi AR0821 Pathology Came a se so – a Backside Illumi ated CMOS device with a 8MP (3848 x 2168) a ay, 2.1 µm pixel pitch, a d 1/1.7-i ch optical fo mat. Key specificatio s: Se so : O semi AR0821 BSI CMOS | Resolutio : 8MP (3848 x 2168) | I te face: USB 3.2 UVC | Le s Mou t: M12 S-Mou t | Dy amic Ra ge: >90 dB (LI-HDR) | Platfo m: Wi dows, Li ux, A d oid. As a 4K Mic oscope USB Came a with Li ea HDR dy amic a ge exceedi g 90 dB, the module ha dles the full illumi atio a ge of cli ical b ightfield a d fluo esce ce imagi g without pe -f ame exposu e adjustme t. Vadzo Imagi g supplies the 8MP Pathology USB Came a as a OEM compo e t eady fo i teg atio i to cli ical imagi g i st ume ts, labo ato y wo kstatio s, a d slide sca i g platfo ms. The module ope ates as a Digital Mic oscopy Came a withi compact i st ume t assemblies a d as a 4K Pathology Came a efe e ce platfo m fo medical imagi g p oduct developme t, with M12 S-Mou t le s i te face accepti g sta da d C-mou t mic oscope elay adapte s fo di ect coupli g to t i ocula mic oscope outputs.
“The Falco -821CRS add esses a clea equi eme t i pathology a d labo ato y mic oscopy fo a came a module that ha dles the illumi atio dy amics of both b ightfield a d fluo esce ce wo kflows without sac ifici g colo accu acy o esolutio . By ce te i g the desig o the O semi AR0821 with LI-HDR a d a Backside Illumi ated pixel a chitectu e, we a e delive i g a solutio that OEM e gi ee s a d cli ical i st ume t develope s ca deploy with co fide ce ac oss a a ge of slide imagi g, cytology, a d tissue a alysis applicatio s.” – Alwi Vi ce t, P oduct Ma age at Vadzo Imagi g.
The Falco -821CRS Mic oscope USB Came a is available ow th ough Vadzo Imagi g fo OEM i teg atio , labo ato y evaluatio , a d cli ical i st ume t developme t. E gi ee i g teams a d p ocu eme t co tacts ca equest p oduct samples, tech ical specificatio s, i teg atio docume tatio , a d applicatio e gi ee i g suppo t.
Vadzo Imagi g is a embedded visio came a ma ufactu e specializi g i high- esolutio , applicatio -optimized came a modules fo i dust ial, medical, automotive, a d scie tific ma kets. The compa y develops USB 3.2, MIPI CSI-2, a d GigE-based came a solutio s built o leadi g image se so platfo ms f om O semi, So y, a d othe Tie 1 se so ve do s. Vadzo Imagi g’s p oducts se ve OEM e gi ee s a d system i teg ato s equi i g p oductio – eady came a modules with platfo m-specific optimizatio s fo edge AI, machi e visio , obotics, a d cli ical imagi g applicatio s.